Benzedrine was the first brand of amphetamine to be introduced in the United States in the 1930s. Its popularity skyrocketed. Doctors prescribed it for a range of ailments ranging from depression to narcolepsy.
At the time, the medication’s effects were not completely understood. As amphetamine’s medical use rose, so did the drug’s misuse.
In the 1880s, a Romanian scientist discovered amphetamine for the first time. According to some reports, it was found in the 1910s. It wasn’t until decades later that it was developed as a medicine.
Smith, Kline, and French, a pharmaceutical company, marketed benzedrine for the first time in 1933. It was a decongestant inhaler sold over the counter (OTC).
In 1937, Benzedrine sulfate, a pill form of amphetamine, was introduced. It was recommended by doctors for the following reasons:
Narcolepsy, anxiety, and extreme fatigue are some of the other symptoms.
The drug’s popularity grew. During WWII, warriors used amphetamine to stay awake, retain mental focus, and prevent fatigue.
Amphetamine raises the levels of dopamine and norepinephrine in the brain. These brain chemicals, among other things, are responsible for pleasure experiences.
Increased dopamine and norepinephrine assist in:
- attention
- focus
- energy
- to curb impulsiveness

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